Studies on the Blood Pressure-Sensitive Receptors in the Rabbit Kidney in Vivo

1) Spontaneous afferent discharges were recorded from nerve fibers dissected from the renal nerves in vivo.2) Raising the systemic blood pressure by mechanical and chemical means caused an increase in the discharge rate. It decreased with a reduction in the systemic blood pressure by mechanical or reflex means.3) The time course of the change in the discharge rate has a strong resemblance to that of the systemic blood pressure.4) The afferent discharge rate was approximately proportional to the systemic blood pressure levels.5) The afferent discharge pattern was irregular and asynchronous with the heartbeat.6) It is concluded that these renal receptors send information about blood pressure levels in the renal artery to the central nervous system.