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Supports nitric oxide research in renal models; should not yet change clinical practice in critical care.
Summary Over the past ten years, nitric oxide has been shown to be important in a number of biological systems. This article is a review of the literature on nitric oxide and its affects on hemodynamics in the kidney. Nitric oxide is a major contributor to basal vasodilatory tone in the renal vasculature and systemic vasculature. It also has effects on the mechanisms which comprise the tubuloglomerular feedback loop. (Vet Emerg & Crit Care, 1998; 8: 7–18)
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Rieser et al. (1998) studied this question.
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