Adenosis (Atypical Adenomatous Hyperplasia): Histopathology and Relationship to Carcinoma

Adenosis is a specific histologic entity which is most frequently seen in transurethral resection of the prostate, although increasingly identified on needle biopsy. The distinction of adenosis from low-grade adenocarcinoma is based on a constellation of histologic features, rather than on any one specific feature (i.e. nucleoli). Although mimicking low grade adenocarcinoma, adenosis has not been shown to be related to adenocarcinoma.