Why the study?
Can 99Tcm-polyphosphate and a computer data collection system be used to quantitatively assess femoral head activity in Legg-Calve-Perthes' disease?
Can 99Tcm-polyphosphate and a computer data collection system be used to quantitatively assess femoral head activity in Legg-Calve-Perthes' disease?
Quantitative assessment using 99Tcm-polyphosphate provides a reliable method for measuring early abnormal femoral head activity in Legg-Calve-Perthes' disease.
May enable quantitative scintigraphic monitoring of femoral head activity in Legg-Calvé-Perthes disease; leaves open prospective validation before clinical use.
Abnormal femoral head activity in Legg-Calve-Perthes' disease has been measured using 99Tcm -polyphosphate and a gamma camera/computer data collection system. A reference point on the data matrix, which is unaffected by the diease, is used for deriving comparative uptake ratios in each femoral head. The reference point remains unaltered after surgical procedures or short intervals between follow-up studies. Early abnormality can be measured in both unilateral and bilateral femoral head pathology.
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Dowsett et al. (1976) studied this question.