There has been a revolution in antidepressant medication over the last ten years, beginning with the introduction to Australia offluoxetine in 1987. Subsequently a further seven new agents (citalopram, fluvoxamine, moclobemide, nefazodone, paroxetine, sertraline, and venlafaxine) have become available. All these newer agents have fewer side effects than earlier agents. The greatest impact of this revolution has been in the treatment of the elderly, who are particularly sensitive to medication side effects. This review examines all antidepressant agents currently available in Australia, and their role in treating depression and other disorders in the elderly.
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Richard Bonwick (1998) studied this question.
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