We develop a self-consistent calculation of the probability of base pair opening from room temperature through the critical behavior at melting for poly(dA)⋅poly(dT). The method uses as input only force constants and interaction potential parameters refined at room temperature plus one parameter describing the open state.
No takes yet. Share an insight, caveat, or question.
Chen et al. (1991) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: