January 1, 2007Neuroepidemiology
Lost Life Years Attributable to Stroke among Patients with Nonvalvular Atrial Fibrillation: A Nationwide Population-Based Follow-Up Study
Why the study?
Does incident stroke increase lost life years in patients with nonvalvular atrial fibrillation?
Population
Patients aged 40-89 years with an incident hospital diagnosis of nonvalvular atrial fibrillation or flutter…
Comparison
Incident stroke of any type vs No incident stroke
Design
Cohort
Follow-up
up to 20 years
Authors
Discussion
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Member takes
Implication
Stroke after AF diagnosis was associated with major life-years lost; leaves open whether earlier prevention alters trajectories in observational cohorts.
Structured PICO
Does incident stroke increase lost life years in patients with nonvalvular atrial fibrillation?
P
Population
Patients aged 40-89 years with an incident hospital diagnosis of nonvalvular atrial fibrillation or flutter, with no previous or concomitant diagnosis of stroke or heart valve disease, from the Danish National Registry of Patients (1980-2002).
I
Intervention
Incident stroke of any type (ischemic and/or hemorrhagic)
C
Comparator
No incident stroke
O
Outcome
Lost life years (excess mortality) attributable to incident stroke within 20 years after a first diagnosis of atrial fibrillationhard clinical
Incident stroke in patients with nonvalvular atrial fibrillation is associated with a substantial loss of life years, particularly in younger patients, women, and those experiencing stroke early after AF diagnosis.
Cite This Study
Frost et al. (2007) studied this question.