The free-space broadband functional near-infrared (fNIR) spectroscopy technique has been used to clinically measure the optical properties of ganglion cysts and lipoma tumors. The NIR system measures the broadband (30MHz-1000MHz) insertion loss (IL) and the insertion phase (IP) of the modulated light. This helps to characterize and model the different penetration depth and path-related modulated photon movement to perform spectroscopic imaging of six patients with right-hand wrist tumors (both ganglion and lipomas). The study is divided into two stages. The first stage is dedicated to performing IL and IP measurements over 30MHz-1000MHz in back-scattering, while in the second stage of broadband measurements using the forward scattering is to extract the ganglion cyst optical absorption and scattering parameters to confirm the diagnosis. The result of the second stage is then used to perform 3D numerical simulation using multi-physics tool (COMSOL).
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Sultan et al. (2017) studied this question.
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