Why the study?
An unexpected rise in post-MI VSD incidence occurred during the COVID-19 pandemic, likely driven by delays in seeking treatment.
Did the COVID-19 pandemic increase the incidence of post-myocardial infarction ventricular septal defects compared to pre- and post-pandemic periods?
Did the COVID-19 pandemic increase the incidence of post-myocardial infarction ventricular septal defects compared to pre- and post-pandemic periods?
The COVID-19 pandemic was associated with a transient increase in post-MI VSD cases, likely driven by delays in seeking treatment, highlighting the critical need for timely reperfusion.
Ventricular septal defect (VSD) is a serious complication of myocardial infarction (MI), with its global incidence significantly reduced in recent years due to advances in coronary reperfusion techniques. However, during the COVID-19 pandemic, there was an unexpected rise in the incidence of post-MI VSD, likely driven by delays in seeking treatment. This study retrospectively analyzed 10 cases of post-MI VSD treated at our hospitals from March 2018 to August 2023, comparing incidence rates across pre-pandemic, pandemic, and post-pandemic periods. The findings revealed a notable increase in VSD cases during the pandemic, with six cases occurring in two years, compared to only two cases in each of the pre-pandemic and post-pandemic periods. Despite these fluctuations, surgical intervention remained a crucial and effective treatment, with 60% of patients surviving the 30-day follow-up. The study underscores the impact of delayed treatment on VSD incidence during the pandemic and highlights the critical need for timely medical intervention to manage severe MI complications effectively.
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Nasso et al. (2025) studied this question.
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