We acknowledge the excellent technical assistance of Miss Diane Orton and Mr. S. Brown, and thank the Medical Research Council for a grant to M. F. D., the Arthritis and Rheumatism Council, the Wellcome Trust and the Spastics Society for financial support. The clinical work described, for which the informed consent of the patients was obtained, was carried out with the full approval of the Ethical Committee of Guy's Hospital Medical School.
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McDevitt et al. (1973) studied this question.