Key result
Postoperative troponin elevation strongly predicted in-hospital cardiac complications (OR 11.3) in older patients undergoing emergency orthopaedic surgery.
Observational (n=187)
Single-blind (ECG interpretation)
No
Postoperative troponin elevation is a superior predictor of cardiac complications compared to ECG changes after emergency orthopaedic surgery, as most myocardial injuries in this setting are silent and occur without concomitant ECG abnormalities.
May support postoperative troponin surveillance in older emergency orthopaedic patients; extends observational data but leaves open efficacy in randomized trials.
INTRODUCTION: The relationship between electrocardiograph (ECG) changes and troponin levels after the emergency orthopaedic surgery are not well characterised. The aim of this study was to determine the correlation between ECG changes (ischaemia or arrhythmia), troponin elevations perioperatively and cardiac complications. MATERIALS AND METHODS: One hundred and eighty-seven orthopaedic patients over 60 years of age were prospectively tested for troponin I and ECGs were performed on the fi rst 3 postoperative mornings or until discharge. RESULTS: The incidences of pre- and postoperative troponin elevation were 15.5% and 37.4% respectively, the majority were asymptomatically detected. Most of the patients who sustained a troponin rise did not have any concomitant ECG changes (51/70 or 72.9%). Postoperative ECG changes were noted in 18.4% (34/185) and of those with ECG changes, slightly more than half (55.9%) had a troponin elevation. Most ECG changes occurred on postoperative day 1 and were non-ST elevation in type. ECG changes occurred more frequently with higher troponin levels. Postoperative troponin elevation (P = 0.018) and not preoperative troponin level (P = 0.060) was associated with ECG changes on univariate analysis. Two premorbid factors were predictors of postoperative ECG changes using multivariate logistical regression; age [odds ratio (OR), 1.05; 95% CI, 1.005 to 1.100, P = 0.029) and sex OR, 2.4; 95% CI, 1.069 to 5.446, P = 0.034). Twenty patients sustained postoperative cardiac complications; 9 (45%) were associated with ECG changes and 16 (80%) with postoperative troponin elevation. Pre- or postoperative troponin elevation better predicted cardiac complications compared with preoperative ECG changes. CONCLUSION: Electrocardiograph changes do not necessarily accompany troponin elevations after the emergency orthopaedic surgery but are more likely to have higher troponin levels. The best predictor of postoperative cardiac complications is troponin elevation.
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Chong et al. (2013) conducted an observational in Emergency orthopaedic surgery (n=187). Postoperative troponin elevation vs. Normal postoperative troponin was evaluated on Postoperative cardiac complications (OR 11.3, 95% CI 2.4-53.1, p=0.002). Postoperative troponin elevation strongly predicted in-hospital cardiac complications (OR 11.3) in older patients undergoing emergency orthopaedic surgery.
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