Macroporous poly(N-isopropylacrylamide) (PNIPA) hydrogels with improved temperature sensitivity were prepared in aqueous glucose solutions. Compared with the conventional PNIPA hydrogel prepared in water, the gels thus prepared showed significantly faster response as the temperature increased above the lower critical solution temperature. The improved properties were due to the macroporous structure, that was formed during gel preparation caused by the phase separation in glucose solutions.
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Zhang et al. (2003) studied this question.
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