Key result
Intravenous injection of 12 mg adenosine identified sick sinus syndrome with 100% sensitivity and 90% specificity, with significantly prolonged post-adenosine corrected sinus node recovery time in patients compared to controls (4005 vs 216 msec, p<0.01).
Why the study?
Does intravenous adenosine injection accurately diagnose sick sinus syndrome compared to standard invasive testing?
Case-Control (n=45)
No
Does intravenous adenosine injection accurately diagnose sick sinus syndrome compared to standard invasive testing?
Intravenous adenosine injection is a highly sensitive and specific alternative to invasive electrophysiological testing for diagnosing sick sinus syndrome.
Answers are grounded in this paper and cite their sources.
May support noninvasive adenosine testing for sick sinus syndrome diagnosis; leaves open prospective validation before replacing invasive studies.
No abstract yet. The journal hasn't published one we can show.
No takes yet. Share an insight, caveat, or question.
Eum et al. (2001) conducted a case-control in Sick sinus syndrome (n=45). Intravenous adenosine vs. Controls without sick sinus syndrome was evaluated on Post-adenosine corrected sinus node recovery time (ADO-CSNRT) after 12 mg adenosine (p=<0.01). Intravenous injection of 12 mg adenosine identified sick sinus syndrome with 100% sensitivity and 90% specificity, with significantly prolonged post-adenosine corrected sinus node recovery time in patients compared to controls (4005 vs 216 msec, p<0.01).
Synapse has enriched 10 related papers. Consider them for comparative context: