Key result
Inherited prothrombotic defects were detected in 28% of patients with Budd-Chiari syndrome and 15% of patients with portal vein thrombosis.
Why the study?
What is the prevalence of inherited prothrombotic defects in patients with Budd-Chiari syndrome and portal vein thrombosis in North India?
Population
105 patients (57 with Budd-Chiari syndrome and 48 with portal vein thrombosis) from North India
Design
Cross-sectional
Authors
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Supports selective thrombophilia testing in BCS/PVT; leaves open whether results alter management or outcomes.
Observational (n=105)
What is the prevalence of inherited prothrombotic defects in patients with Budd-Chiari syndrome and portal vein thrombosis in North India?
Absolute Event Rate: 28% vs 15%
Inherited prothrombotic defects are present in a significant proportion of patients with Budd-Chiari syndrome and portal vein thrombosis in North India, with differing mutation profiles between the two conditions.
Bhattacharyya et al. (2004) conducted an observational in Budd-Chiari syndrome and portal vein thrombosis (n=105). Budd-Chiari syndrome vs. Portal vein thrombosis was evaluated on Detection of inherited prothrombotic defects. Inherited prothrombotic defects were detected in 28% of patients with Budd-Chiari syndrome and 15% of patients with portal vein thrombosis.
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