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August 27, 2026Substance Use & Misuse

Associations of Loneliness and Childhood Adversity With ASSIST-Measured Substance Use Risk in a University Student Sample

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Authors

TFTazveen FarihaMFMyriam ForsterTGTimothy J. Grigsby

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Overview

Cross-sectional survey reveals childhood adversity increases substance use risk in college students, highlighting the need for trauma-informed campus care.

Key Points

  • To evaluate the associations between adverse childhood experiences (ACEs), loneliness, and moderate- to high-risk alcohol, cannabis, and tobacco use among university students.
  • Cross-sectional survey conducted in Spring 2024 among 2,393 students at a public university in Southern California.
  • Assessed substance-specific risk using the WHO Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST).
  • Conducted multivariable logistic regression analyses to determine associations with ACEs and evaluate loneliness as a potential moderator.
  • Each additional ACE was associated with increased odds of moderate- to high-risk alcohol use (aOR = 1.15, 95% CI = 1.04–1.27), cannabis use (aOR = 1.16, 95% CI = 1.07–1.25), and tobacco use (aOR = 1.15, 95% CI = 1.04–1.26).
  • Loneliness did not significantly moderate the associations between cumulative ACE exposure and substance use risk across any substance category (all p > 0.05).

Cite This Study

Fariha et al. (2026) studied this question.

synapsesocial.com/papers/6a8fea0110c91c1e92621ec3https://doi.org/10.1080/10826084.2026.2717425
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