Clinical review highlights limitations of lesion-based endpoints in pemphigus vulgaris, suggesting a multidimensional framework tracking toxicity and patient outcomes.
Current remission criteria for pemphigus vulgaris rely on binary, lesion-based endpoints that do not capture immunological status, treatment toxicity, or patient quality of life. We argue for a multidimensional framework incorporating minimal disease activity, validated severity scores, glucocorticoid toxicity indices, and patient-reported outcomes.
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Ahuja et al. (2026) studied this question.
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