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September 26, 2017Pharmacopsychiatry

What Characterizes Depression in Old Age? Results from the Bruneck Study

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Why the study?

What is the prevalence of depression and its impact on quality of life and cognition in older adults?

Population

456 participants from the Bruneck Study 2010, mean age 73.1±8.2 years.

Comparison

Depressive symptoms and antidepressant treatment vs No relevant depressive symptoms

Design

Cross-sectional

Key result

Older adults with depressive symptoms (GDS > 8) had significantly lower quality of life (p<0.001) and cognitive scores (p=0.015) compared to those without relevant depressive symptoms.

Authors

MDMichaela DefrancescoRPRaimund PechlanerSKStefan Kiechl

Discussion

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Overview

Supports routine depression assessment in older adults; leaves open whether treating symptoms improves cognitive and quality-of-life outcomes.

Study Design

Type

Cross-Sectional (n=456)

Structured PICO

What is the prevalence of depression and its impact on quality of life and cognition in older adults?

P
Population
456 older adults (mean age 73.1 years) from the Bruneck Study 2010 assessed for depressive symptoms, cognition, and quality of life.
E
Exposure
Depressive symptoms (Geriatric Depression Scale score > 8) and antidepressant treatment
C
Comparator
No relevant depressive symptoms (Geriatric Depression Scale score ≤ 8)
O
Outcome
Prevalence of depression and characteristics of patients treated with antidepressants (including WHO-QoL and Mini Mental State Examination scores)patient reported

Main Result

p-value: p=<0.001

Depressive symptoms are common in older adults and are associated with significantly reduced quality of life and cognitive function.

Cite This Study

Defrancesco et al. (2017) conducted a cross-sectional in Depression in old age (n=456). Depressive symptoms (GDS > 8) vs. No relevant depressive symptoms (GDS ≤ 8) was evaluated on WHO-QoL and Mini Mental State Examination scores (p=<0.001). Older adults with depressive symptoms (GDS > 8) had significantly lower quality of life (p<0.001) and cognitive scores (p=0.015) compared to those without relevant depressive symptoms.

synapsesocial.com/papers/6a900cdbe8d327d500340cb2https://doi.org/10.1055/s-0043-119417
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