Why the study?
Does prolonged chemotherapy consisting of intermittent doses of streptomycin and daily doses of paraminosalicylic acid or isoniazid improve outcomes in patients with clinically primary tuberculous pericarditis?
Population
27 patients with clinically primary tuberculous pericarditis
Design
Case_series
Follow-up
six months to three years
Authors
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May support chemotherapy in tuberculous pericarditis; leaves open efficacy and constriction prevention without controlled trials.
Does prolonged chemotherapy consisting of intermittent doses of streptomycin and daily doses of paraminosalicylic acid or isoniazid improve outcomes in patients with clinically primary tuberculous pericarditis?
Prolonged chemotherapy with streptomycin and paraminosalicylic acid or isoniazid results in favorable, symptom-free outcomes for the majority of patients with primary tuberculous pericarditis, though progression to constrictive pericarditis or death still occurs in a minority.
Goyette et al. (1954) studied this question.
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