Why the study?
Should women with specific previous pregnancy complications be screened for thrombophilia?
Should women with specific previous pregnancy complications be screened for thrombophilia?
This consensus report provides recommendations for thrombophilia screening in women with a history of severe pregnancy complications.
Answers are grounded in this paper and cite their sources.
Supports targeted thrombophilia screening in women with prior severe pregnancy complications; reinforces Level 1 consensus and directs future management trials.
Summary The implications of currently available data on the association of gestational vascular complications with thrombophilia are presented in this consensus report. Screening is recommended for women with the following previous complications: fetal loss including three or more first trimester loss, two or more second trimester loss, or any stillbirth; early, severe or recurrent preeclampsia and severe intrauterine growth restriction. Maternal antithrombotic therapy is currently evaluated in women with thrombophilia and previous complications. On behalf of the Scientific Subcommittee on Perinatal and Pediatric Hemostasis and Working Group on Women’s health Issues and Standardization Committee of the International Society of Thrombosis and Hemostasis.
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Grabowski et al. (2004) studied this question.
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