The formaldehyde-induced fluorescence method for detection of intracellular catecholamines was applied to neuroblastoma cells in human bone marrow aspirates and cultured cells from human and murine sources. Based upon a conventional staining technique for bone marrow smears, fewer fluorescent cells than expected were detected. The production and storage of detectable amounts of catecholamines may vary with the growth phase of the cell.
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Helson et al. (1973) studied this question.
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