Why the study?
Does age affect the time taken to recover from neuromuscular blockade following tubocurarine use and neostigmine reversal in patients undergoing elective surgery?
Does age affect the time taken to recover from neuromuscular blockade following tubocurarine use and neostigmine reversal in patients undergoing elective surgery?
Age does not appear to significantly affect the recovery time from neuromuscular blockade when using tubocurarine reversed by neostigmine.
Age may not affect recovery times with this regimen; leaves open generalizability to modern agents or randomized settings.
Thirteen young and thirteen elderly patients undergoing elective surgery were given an anaesthetic using tubocurarine as the sole muscle relaxant. Following reversal with neostigmine, the time taken to recover from neuromuscular blockade was measured. No significant difference was found between the two groups of patients.
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Chmielewski et al. (1978) studied this question.
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