Why the study?
Does intravenous synthetic eledoisin alter systemic and coronary hemodynamics in anaesthetized dogs?
Does intravenous synthetic eledoisin alter systemic and coronary hemodynamics in anaesthetized dogs?
Intravenous synthetic eledoisin causes significant hemodynamic depression in intact dogs, with effects resembling those of bacterial endotoxin.
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Warrants caution in animal cardiovascular studies using eledoisin; leaves open translation to human physiology or sepsis models.
George M. Maxwell (1964) studied this question.
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