Bioelectrocatalysis of Methyldopa by Adsorbed Tyrosinase on the Surface of Modified Glassy Carbon with Carbon Nanotubes

In this work, a method for performance of tyrosinase/single-walled carbon nanotubes/glassy carbon (TR/SWCNTs/GC) electrode, prepared by modification of GC electrode surface with SWCNTs and adsorption of tyrosinase on the SWCNT surfaces were investigated. SWCNTs were studied with the help of scanning electron microscopy (SEM). Dimensions of SWCNTs make them ideal candidates for the adsorption of proteins. Copper containing enzyme, tyrosinase, exhibited an electrical contact with electrode, because of structural alignment of enzyme on the SWCNT surfaces. This method has the requisite accuracy, sensitivity and precision and the modified electrode showed good repeatability and stability to assay methyldopa in bulk form and pharmaceutical dosage forms.