Nondepolarizing Muscle Relaxants as an Option in Spine Medicine

Objective. Comparative assessment of clinical results and pharmacological cost-efficiency of muscle relaxant application in spine medicine. Material and Methods. Retrospective (100 patients) and prospective (230 patients) analysis of anesthetic management during elective surgeries in traumatologic-orthopaedic patients was performed. Hemodynamic indices were monitored: SBP, DBP, MAP, HR, gas exchange, breathing mechanics, and neuromuscular conductivity. Pharmacological economic and statistical analyses of muscle relaxant efficiency were performed. Results. Use of only nondepolarizing muscle relaxants provided a high quality of general anesthesia and promoted the process of consciousness recovery, adequate spontaneous respiration through a tracheal tube and reduced the duration of artificial lung ventilation thus reducing a number of complications, and resulted in reduction of monitoring equipment depreciation value and medical staff load. Conclusion. Application of nondepolarizing muscle relaxants can be the option for myoplegia during a general anesthesia in trauma and orthopaedic patients.