Mycosis Fungoides

Mycosis fungoides is one of a family of uncommon cutaneous T-cell lymphomas that includes the Sézary syndrome, tumeur d'emblée, Ki-1–positive lymphoma, and the adult T-cell leukemia or lymphoma caused by the type C retrovirus human T-cell lymphotropic virus Type I. All but mycosis fungoides and the Sézary syndrome can be distinguished by their aggressive presentation, early visceral spread, poor prognosis, unique histologic features, and lymphocytic or retroviral markers.1 Mycosis fungoides and its variant, Sézary syndrome, in which circulating cells are associated with erythroderma, are relatively indolent lymphomas composed of thymus-derived lymphocytes. They have a variable natural history and may remain . . .