Why the study?
Does an erratic INR response indicate late cardiac tamponade in patients on warfarin after valve replacement surgery?
Does an erratic INR response indicate late cardiac tamponade in patients on warfarin after valve replacement surgery?
An erratic INR response in patients on warfarin after valve replacement surgery may be an early indicator of late cardiac tamponade rather than its cause.
Erratic INR may flag late tamponade risk after valve replacement; leaves open causality and needs prospective confirmation.
Two cases of late cardiac tamponade after valve replacement surgery are reported: both patients were treated with oral anticoagulants (warfarin) after operation. An erratic response in the international normalised ratio (INR) was found before the diagnosis of late tamponade. It is suggested that this response of the INR may be an early indicator of late cardiac tamponade rather than a cause.
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Wong et al. (1992) studied this question.
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