Editorial1 July 1954THE WORK OF BREATHING AND ITS RELATION TO RESPIRATORY ACIDOSISRICHARD L. RILEYRICHARD L. RILEYSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-41-1-172 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn a recent review onThe Work of Breathing, Dr. Arthur B. Otis introduces his subject by saying that it "is a topic which occupies one of the quieter spots in the field of physiology."1It is my purpose here to bring the work of breathing into one of the noisier spots in the field of clinical investigation because of its important relationship to the subject of respiratory acidosis. At the present time there is no general agreement as to why the partial pressure of carbon dioxide in the alveolar gas and arterial blood becomes elevated in respiratory acidosis and,...1 Otis AB: The work of breathing, Physiol. Rev. (in press). Google Scholar2 CournandRichardsBaderBaderFishman ADWMERAAP: Oxygen cost of breathing in normal and in chronic pulmonary and cardiac diseases, presented at the 67th annual meeting of The Association of American Physicians, May 4, 1954. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByA single-film fiber optical sensor for simultaneous measurement of carbon dioxide and relative humidityA reflection-mode fibre-optic sensor for breath carbon dioxide measurement in healthcareCO2 Can Be Good for YouOpioids and Benzodiazepines Appear Paradoxically to Delay Inevitable Death after Ventilator WithdrawalPrognostic Value of Hypercapnia in Patients with Chronic Respiratory Failure during Long-term Oxygen TherapyThe Pathophysiology of Weaning FailureVentilatory Control and DyspneaClinical Principles of Positive Pressure VentilationRespiratory Muscle EnergeticsEnergy requirements of the respiratory musculature in asthmaPattern of breathing and carbon dioxide retention in chronic obstructive lung diseasePulmonary Function at Rest and during Exercise in Uncomplicated ObesityAcute Effects of Intermittent Positive Pressure Breathing in Patients with Chronic Obstructive Lung DiseaseA New Stimulant for Ventilatory Failure?Acute Respiratory Failure in the AdultThe Metabolic and Respiratory Acidosis of Acute Pulmonary EdemaARNOLD ABERMAN, M.D., C.M., MILFORD FULOP, M.D., F.A.C.P.Acid Regulation and CO2 RetentionThe Case Against the Use of Respiratory StimulantsA Controlled Study of Three Respiratory Stimulants in Chronic Respiratory FailureDrive and Performance of the Ventilatory Apparatus in Chronic Obstructive Lung DiseaseRespiratory Failure and UnconsciousnessOxygen Therapy in Respiratory FailureStatistical Evaluation of the Action of Three Different Respiratory Analeptics on Pulmonary VentilationCarbon Dioxide Tension and Ventilatory Mechanics in Chronic Obstructive Lung DiseaseBENJAMIN BURROWS, M.D., FRANKLIN B. SAKSENA, M.D., CARL F. DIENER, M.D.Of Seals and MitochondriaVentilatory FailureEvaluation of Respiratory ImpairmentPickwick-SyndromCHANGES OF ARTERIAL CARBON-DIOXIDE TENSION IN PATIENTS WITH CHRONIC LUNG DISEASE BREATHING OXYGENRespiratory stimulants in obstructive lung diseaseMechanisms of chronic carbon dioxide retention in patients with obstructive pulmonary diseaseEffect of a respiratory stimulant on the ventilatory response to carbon dioxide inhalationAn Evaluation of Ethamivan as a Respiratory Stimulant in Barbiturate Intoxication, and Alveolar Hypoventilation in Emphysema and ObesityR. M. CHERNIACK, M.D., F.R.C.P.(C), F.A.C.P., G. YOUNG, M.D.Dichlorphenamide, a potent carbonic anhydrase inhibitorThe Fighter Versus the NonfighterA New Ventilatory Assister for Patients with Respiratory AcidosisEffect of Ethamivan on Alveolar Ventilation in Patients with Chronic Lung DiseaseEffects of a newer respiratory stimulant (vanillic diethylamide) in respiratory acidosis due to obstructive pulmonary emphysema or obesityBibliographyAN ETIOLOGY OF ACUTE RESPIRATORY ACIDOSISFailure to Improve Effective Ventilation on Shifting from Mouth to Tracheostomy Breathing in Clinically Stable EmphysemaDICHLORPHENAMIDE IN CHRONIC RESPIRATORY FAILUREThe Effect of Respiratory Tract Obstruction Upon the Ventilatory Response to Inhaled Carbon Dioxide in Normal Subjects1 1From the Cardio-Pulmonary Laboratory and the Department of Medicine, Mt. Sinai Hospital, Miami Beach, Florida, and the Section of Cardiology of the Department of Medicine, University of Miami School of Medicine, Coral Gables, Florida.,2 2Supported in part by a grant from the Heart Association of Greater Miami, and from the National Heart Institute (H-4249).Die allgemeine Pathologie der äußeren AtmungAtemmechanische Untersuchungen beim schweren obstruktiven LungenemphysemThe use of oxygen therapy and of mechanical aids in the treatment of cor pulmonaleCor pulmonaleCor pulmonaleThe respiratory effects of progesterone in severe pulmonary emphysemaSYNDROME OF EXTREME OBESITY AND HYPOVENTILATION: STUDIES OF ETIOLOGY*JACK D. HACKNEY, M.D., MILTON G. CRANE, M.D., CLARENCE C. COLLIER, M.D., STANLEY ROKAW, M.D., DONALD E. GRIGGS, M.D., F.A.C.P.Mechanics of respiration in bronchial asthmaPulmonary EmphysemaDyspnea and the work of breathing in diseases of the heart and lungsRespiratory acidosis in chronic pulmonary heart disease: Pathogenesis, clinical features and managementThe cardiorespiratory syndrome related to obesity: Clinical manifestations and pathologic physiologyThe syndrome of alveolar hypoventilationZur Behandlung des Lungenemphysems mit chronischer respiratorischer AcidoseA peculiar type of cardiopulmonary failure associated with obesityThe application of respiratory physiology to therapeutic procedures in pulmonary emphysemaVentilatory drive in chronic pulmonary emphysema 1 July 1954Volume 41, Issue 1Page: 172-176KeywordsBreathingPartial pressure of carbon dioxideRespiratory physiology Issue Published: 1 July 1954 PDF DownloadLoading ...
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Richard L. Riley (1954) studied this question.