(S)-(+)-2-(α-Hydroxybenzyl)benzimidazole (1) and (S)-(-)-2-benzimidazole-1-ethanol (2) were synthesised and converted to chiral borohydrides which reduced prochiral ketones to the corresponding chiral alcohols in high yields (80 to 100%, e.e. 42 to 95%). This is the first report of sodium borohydride modified by 1,2-amino alcohol.
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Maiti et al. (1998) studied this question.
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