Key result
Pure rheumatic mitral stenosis was associated with a 17% prevalence of mitral valve prolapse, which is higher than the 3% to 5% rate reported for the general population.
Observational (n=112)
Mitral valve prolapse is present in 17% of patients with pure rheumatic mitral stenosis, a rate much higher than the general population, suggesting rheumatic mitral stenosis plays a direct role in its genesis.
Association warrants echocardiographic vigilance for prolapse in rheumatic mitral stenosis; leaves open causal mechanisms and clinical impact.
Of 122 adult patients suspected of having rheumatic mitral stenosis, 112 fulfilled the hemodynamic and angiographic criteria for pure, isolated mitral stenosis. There were 88 females and 24 males with an age range of 16 to 60 years. The left ventriculograms (30 degrees right anterior oblique) were subjectively assessed for gross bulging of the mitral valve leaflets beyond the mitral fulcrum into the left atrium during a beat with maximal opacification. Seventeen percent of cases had typical evidence of mitral valve prolapse, which is much higher than the 3% to 5% rate reported for the general population. This phenomenon was independent of the patients' age, sex, hemodynamic findings, and/or their underlying cardiac rhythm, thus implying the direct role of rheumatic mitral stenosis in the genesis of secondary mitral valve prolapse.
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Rezaian et al. (2001) conducted an observational in Pure rheumatic mitral stenosis (n=112). Pure rheumatic mitral stenosis vs. General population was evaluated on Evidence of mitral valve prolapse on left ventriculogram. Pure rheumatic mitral stenosis was associated with a 17% prevalence of mitral valve prolapse, which is higher than the 3% to 5% rate reported for the general population.
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