Key result
A protocol-personalized approach to hemodynamic management during abdominal surgeries in elderly patients reduced MACE outcomes (RR 0.462; 95% CI 0.251-0.850; p=0.038) compared to standard management.
Why the study?
To evaluate the efficacy and safety of a modified protocol-personalized approach to hemodynamic management during abdominal surgery in elderly and senile patients.
Does a protocol-personalized approach to hemodynamic management improve MACE outcomes in elderly patients undergoing abdominal surgeries?
RCT
randomized
Does a protocol-personalized approach to hemodynamic management improve MACE outcomes in elderly patients undergoing abdominal surgeries?
A protocol-personalized approach to perioperative hemodynamic management reduces MACE and arrhythmias in elderly patients undergoing abdominal surgery.
Answers are grounded in this paper and cite their sources.
May reduce MACE and arrhythmias in elderly abdominal surgery patients; extends RCT evidence for protocol-personalized hemodynamic management.
One of the options for solving the problem of a “non-standard” patient undergoing a major and traumatic operation, perhaps, is the protocol-personalized approach to hemodynamic management. The objective: to study the efficacy and safety of using a modified protocol-personalized approach to hemodynamic management during surgical interventions on abdominal organs in elderly and senile patients. Subjects and Methods. A randomized prospective-retrospective clinical trial was conducted in parallel groups: Group 1 (control) - standard management of the perioperative period; Group 2 - standard management supplemented by the protocol-personalized approach to hemodynamic management. Results. Patients in the main group had the best parameters as per MACE outcomes (RR: 0.462, [95% CI: 0.251-0.850] p = 0.038). In the intra- and postoperative period, patients in the control group had a relatively higher risk of arrhythmias (RR: 2.517 [95% CI: 1.218; 5,200] p = 0.017). Conclusion. The use of the protocol-personalized approach results in better MACE outcomes (RR: 0.462, 95% CI: 0.251-0.850; p = 0.038) during surgical interventions on the abdominal organs in elderly and senile patients, and also, reduces the risk of arrhythmias (RR: 2.517, 95% CI:1.218; 5.200) p = 0.017.
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Kharlamov et al. (2021) conducted an RCT in abdominal surgeries. protocol-personalized approach to hemodynamic management vs. standard management was evaluated on MACE outcomes (RR 0.462, 95% CI 0.251-0.850, p=0.038). A protocol-personalized approach to hemodynamic management during abdominal surgeries in elderly patients reduced MACE outcomes (RR 0.462; 95% CI 0.251-0.850; p=0.038) compared to standard management.
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