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Three patients with sudden, unmanageable exacerbation of acne vulgaris were shown to have Gram-negative folliculitis due toPseudomonas aeruginosa.In each patient, the source of thePseudomonasproved to be an otitis externa infection. In contrast to previous cases of Gram-negative folliculitis due toProteus, Escherichia coli, orKlebsiella, the anterior nares were not colonized. Treatment of the otitis externa and the Gram-negative folliculitis with acetic acid compresses and topical antibiotics led to prompt resolution without recurrence. (Arch Dermatol115:1203-1204, 1979)
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A 1979 study studied this question.
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