Canine malignant lymphoma: A review and comparison with human non‐hodgkin's lymphoma

the Netherlands being 1.2 million dogs, this suggests a minimum incidence rate of 33 per 100,000 dogs, but the real incidence of canine NHL in the Netherlands must be much higher.Although a female predominance was observed by some authors (8,9), no sex predilection was revealed in most studies (6,15), including ours (Table 1).In humans the incidence of NHL is slightly but consistently higher in men than in women ( 16).Lymphomas affect dogs of all ages but predominantly those in middle-age.The mean age of dogs with NHL has been reported to vary from 6.3 to 7.7 years (6,9,12,13,15).This is in agreement with our epidemiological study at the UUCCA in which the median age of the 254 dogs with NHL was 6.6 years and the age distribution was similar for both sexes.Age-specific incidence rates have been calculated in the USA and found to increase from 1.5/100,000 for dogs less than 1 year of age to more than 80/100,000 for dogs 10 years of age (7).This is comparable to the age distribution of NHL