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January 1, 1995Journal of VirologyOpen Access

Expression of the human immunodeficiency virus type 1 (HIV-1) nef gene during HIV-1 production increases progeny particle infectivity independently of gp160 or viral entry

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Authors

MMMichael D. MillerWyższa Szkoła Hotelarstwa i GastronomiiMWM T WarmerdamGladstone InstitutesKPKimberly PageUniversity of New Mexico

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Miller et al. (1995) studied this question.

synapsesocial.com/papers/6a903a2c6bfd95d7bd4dd220https://doi.org/10.1128/jvi.69.1.579-584.1995
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene1994 · 370 citations
  2. 2Severe immunodeficiency associated with a human immunodeficiency virus 1 NEF/3'-long terminal repeat transgene.1994 · 87 citations
  3. 3CD4 is retained in the endoplasmic reticulum by the human immunodeficiency virus type 1 glycoprotein precursor1990 · 228 citations
  4. 4The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes.1994 · 400 citations
  5. 5The negative effect of human immunodeficiency virus type 1 Nef on cell surface CD4 expression is not species specific and requires the cytoplasmic domain of CD41993 · 113 citations