The toxinotyping and the antimicrobial susceptibility of Clostridium perfringens strains isolated from chicken with necrotic enteri- tis were determined. All the 22 C. perfringens belonged to toxinotype A and the MIC values to 14 antimicrobial agents showed that all strains were susceptible to amoxicillin, amoxicillin-clavulanic acid, cefoxitin, chloramphenicol, enrofloxacin, metronidazole and penicillin- streptomycin. Most strains showed high rates of resistance to erythromycin, cephalexin and bacitracin and sulfaquinolaxin. Our results suggest an important role of the α-toxin in the pathogenesis of necrotic enteritis and new strategies for preventing and controlling the Clos- tridium perfringens infection in poultry need to be investigated.
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Llanco et al. (2012) studied this question.
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