Key result
A positive SARC-F score (≥4) was independently associated with longer hospital stay (OR 2.34; 95% CI 1.09-5.04) and hospital readmission (OR 3.73; 95% CI 1.60-8.69) after a cardiovascular event.
Why the study?
Few studies have focused on sarcopenia after an acute cardiovascular event, and the use of the SARC-F screening questionnaire to predict adverse outcomes in these patients remains uninvestigated.
Does a positive SARC-F score predict adverse outcomes in patients admitted with a suspected infarction?
Cohort (n=180)
Does a positive SARC-F score predict adverse outcomes in patients admitted with a suspected infarction?
The SARC-F screening questionnaire identifies post-acute cardiovascular event patients at risk for sarcopenia, which is associated with longer hospital stays and higher readmission rates.
SARC-F positivity flags higher readmission risk post-event; supports trials before routine screening changes practice.
It is already established that sarcopenia is associated with adverse outcomes; however, few studies have focused on patients who have suffered an acute cardiovascular event. The use of SARC-F, a 5-item sarcopenia screening questionnaire, in these patients remains to be investigated. We aimed to investigate whether SARC-F can predict adverse outcomes in patients admitted to a hospital with a suspected infarction. This is a 1-year prospective cohort study. During hospitalization, patients completed the SARC-F questionnaire (scores ≥ 4 considered positive for the risk of sarcopenia). Length of hospital stay (LOS), new hospital admission, myocardial infarction, and cardiovascular mortality were collected via medical records and phone interviews. In total, 180 patients were evaluated. The median age was 60.6 years; 72.3% of the participants were men, and half of the sample had comorbidities. The median SARC-F score was 1.0 (interquartile range, 0–3.0), and 21.1% of the participants screened positive. Risk of sarcopenia was independently associated with longer LOS (odds ratio, 2.34; 95% CI, 1.09–5.04; p = 0.030) and hospital readmission (odds ratio, 3.73; 95% CI, 1.60–8.69; p = 0.002). One-fifth of post-acute cardiovascular event patients in this cohort screened positive for sarcopenia using the SARC-F screening questionnaire. Positive scores were associated with a longer LOS and hospital readmission.
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Fayh et al. (2022) conducted a cohort in Suspected infarction / post-acute cardiovascular event (n=180). Risk of sarcopenia (SARC-F score ≥ 4) vs. No risk of sarcopenia (SARC-F score < 4) was evaluated on Hospital readmission (OR 3.73, 95% CI 1.60-8.69, p=0.002). A positive SARC-F score (≥4) was independently associated with longer hospital stay (OR 2.34; 95% CI 1.09-5.04) and hospital readmission (OR 3.73; 95% CI 1.60-8.69) after a cardiovascular event.
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