Key result
In geriatric patients with NSTEMI, a one-point increase in creatinine clearance was independently associated with a reduced risk of one-year mortality (HR 0.973).
Why the study?
Renal insufficiency is linked to high mortality in acute coronary syndrome, but studies have often excluded advanced-age patients with renal insufficiency.
Observational (n=537)
Yes
In geriatric patients (aged ≥65 years) with NSTEMI, lower creatinine clearance, reduced LVEF, and the absence of coronary revascularization are independent predictors of one-year all-cause mortality.
Answers are grounded in this paper and cite their sources.
Renal insufficiency may flag higher mortality risk in elderly NSTEMI; leaves open whether interventions improve outcomes.
Objectives: Although renal insufficiency is associated with high mortality in patients with acute coronary syndrome, studies have often excluded patients of advanced age who have renal insufficiency. The present study aimed to determine the relationship between renal insufficiency and mortality predictors in patients with non-ST-segment elevation myocardial infarction (NSTEMI) who were aged 65 and older.
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Pınar Demir Gündoğmuş (2021) conducted an observational in Non-ST-segment elevation myocardial infarction (NSTEMI) (n=537). Creatinine clearance vs. Lower creatinine clearance was evaluated on One-year mortality (HR 0.973, 95% CI 0.954-0.991, p=0.005). In geriatric patients with NSTEMI, a one-point increase in creatinine clearance was independently associated with a reduced risk of one-year mortality (HR 0.973).
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