Target Animal Safety and Residual Study for Berberine and other Phytogenic Compounds in Broiler Chickens

Background: Phytogenic compounds are one of many alternatives to current industry feed ingredients for the poultry industry. However, despite increased reports on the activity of phytogenic compounds against disease in poultry, there is a lack of data regarding safety and residual toxicity. This two-part study investigated the general health of broiler chickens fed Berberine, Ursolic Acid, Piceid, Honokiol and Baicalin in-feed at three different levels, and assessed the poultry tissue residue of Berberine in breast muscle, upper and lower thigh, and liver through LC/MS-MS.