The host response to titanium and its alloys is not always favorable, as a fibrous layer may form at the skeletal tissue-device interface, causing aseptic loosening. Therefore, a great deal of current orthopedic research is focused on developing implants with improved osseointegration properties in order to increase their clinical success. Promising new studies have been reported regarding coating the currently available implants with various coating materials and techniques so as to improve the long-term stability of implants. This article will discuss various coating materials developed, their advantages and disadvantages as coating materials and their biological performance.
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Ramaswamy et al. (2009) studied this question.
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