D-Adenosine-5'-phosphorimidazolide reacts very much more rapidly with D-adenosine than with L-adenosine on a poly-D-uridylic acid template. This permits the partial resolution of DL-adenosine. These experiments suggest that segregation of D- and L-nucleotides may have occurred at an early stage in biochemical evolution.
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Schneider-Bernloehr et al. (1968) studied this question.
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