Key result
Periostin expression was observed in 31.3% of malignant mammary tumours and 12.5% of benign tumours in female dogs, correlating positively with the degree of histological malignancy.
Why the study?
Periostin has a significant role in tumor cell proliferation, migration, and progression, but its expression in malignant and benign mammary gland tumors of female dogs required determination.
Observational (n=114)
Absolute Event Rate: 31.3% vs 12.5%
Hypothesis-generating for POSTN in canine mammary tumors; leaves open its diagnostic or prognostic utility.
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Borecka et al. (2020) conducted an observational in Mammary gland tumours (n=114). Periostin (POSTN) expression vs. Benign tumours was evaluated on POSTN expression. Periostin expression was observed in 31.3% of malignant mammary tumours and 12.5% of benign tumours in female dogs, correlating positively with the degree of histological malignancy.
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