Why the study?
Does the CardioQP oesophageal Doppler accurately measure cardiac output compared to thermodilution in paediatric patients with congenital heart defects?
Does the CardioQP oesophageal Doppler accurately measure cardiac output compared to thermodilution in paediatric patients with congenital heart defects?
Cardiac output values measured by CardioQP oesophageal Doppler do not reliably represent cardiac output compared with thermodilution in children, suggesting a need for individual aortic diameter measurement to improve performance.
CardioQP shows only moderate agreement with thermodilution in paediatric congenital heart disease; leaves open whether patient-specific aortic calibration improves reliability.
The minimally invasive CardioQP oesophageal Doppler probe estimates cardiac output by measuring blood flow velocity in the descending aorta. Individual variables to enter are patient's age, weight and height. We measured cardiac output simultaneously with CardioQP and pulmonary artery catheter thermodilution techniques during heart catheterisation in 40 paediatric patients with congenital heart defects. Median [range] age was 8.2 years [0.5-16.7 years], cardiac output values measured by thermodilution and CardioQP were 3.6 l.min(-1) [1.2-7.1 l.min(-1)] and 3.0 l.min(-1) [0.7-6.7 l.min(-1)], respectively. These values showed only moderate correlation (r = 0.809; p < 0.0001). Bias and precision were 0.66 l.min(-1) and 1.79 l.min(-1) (95% limits of agreement: -1.13 to +2.45 l.min(-1)). Based on our preliminary experience, cardiac output values measured by CardioQP in children do not reliably represent cardiac output values compared with the thermodilution technique. We suggest measurement of individual aortic diameter to improve performance of the CardioQP.
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Knirsch et al. (2008) studied this question.
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