The effect of vitamin D on the components of epiphyseal cartilage was investigated. Three-week-old rachitic chicks were pooled into two groups, one of which received vitamin D3, while the other served as a control. The epiphyseal cartilage from these two groups was subjected to comparative study which is described in detail. Two distinct effects that resulted from the vitamin D3administration were the significant increases in the hexosamine content and in the amount of acetone-extractable solids.
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Cipera et al. (1960) studied this question.
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