Key result
Parvovirus B19 infection was linked to 32 of 65 cases of paediatric acute myocarditis in Italy, with 29 children requiring intensive care and 8 fatalities overall.
Why the study?
Acute myocarditis has risen among paediatric patients in Italy, with cases linked to parvovirus B19 infection during a concurrent European outbreak.
Observational (n=65)
Yes
Highlights a severe outbreak of parvovirus B19-associated paediatric myocarditis in Italy with high rates of intensive care admission and mortality, underscoring the need for timely diagnosis and standardized treatment.
B19V-linked pediatric myocarditis surge warrants heightened surveillance; leaves open IVIG benefit in severe cases.
Acute myocarditis has risen among paediatric patients in Italy, with 65 clinically suspected cases reported by 12 centres in 2024, 32 linked to parvovirus B19 (B19V) infection. In 11 cases, B19V was not ruled out despite a concurrent European outbreak. Twenty-nine children required intensive care; eight fatalities occurred. While effective for both severe B19V infection and myocarditis, intravenous immunoglobulins were given in only one-third of cases. These findings highlight the need for timely diagnosis, stronger surveillance, and standardised treatment protocols.
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Poeta et al. (2024) conducted an observational in Acute myocarditis (n=65). Parvovirus B19 (B19V) infection was evaluated on Intensive care requirement and fatalities. Parvovirus B19 infection was linked to 32 of 65 cases of paediatric acute myocarditis in Italy, with 29 children requiring intensive care and 8 fatalities overall.
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