Answers are grounded in this paper and cite their sources.
The concept of molar efficiency is introduced as a new metric to enable assessment of reaction efficiency in discovery medicinal chemistry. Calculations from molar units enable cross-comparison of the broad range of transformations employed in discovery-phase medicinal chemistry research and is proposed to facilitate identification of more sustainable synthetic transformations.
No takes yet. Share an insight, caveat, or question.
McGonagle et al. (2013) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: