Studies of Iron Metabolism in a Case of Hemochromatosis

Article1 April 1939STUDIES OF IRON METABOLISM IN A CASE OF HEMOCHROMATOSISALEXANDER MARBLE, F.A.C.P., RACHEL M. SMITHALEXANDER MARBLE, F.A.C.P., RACHEL M. SMITHAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-12-10-1592 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn connection with the clinical study and care of patients with hemochromatosis seen in this clinic,1 it seemed desirable to investigate the iron metabolism by means of balance studies. This was thought particularly worthwhile because of the paucity of such data in the literature. Only four reports have come to our attention, namely those of Howard and Stevens,2 McClure,3 Dry4 and Fowler and Barer.5CASE REPORTMr. F. H. was first seen on August 2, 1933 when 47.6 years of age. Sugar had been found in his urine first in August 1931 and from his history it was estimated that...Bibliography1. MARBLE A: Hemochromatosis. A report of 17 cases, including 2 in women. (To be published.) Google Scholar2. HOWARDSTEVENS CPFA: The iron metabolism of hemochromatosis, Arch. Int. Med., 1917, xx, 896. CrossrefGoogle Scholar3. MCCLURE CW: Metabolism in a case of hemochromatosis, Arch. Int. Med., 1918, xxii, 610. CrossrefGoogle Scholar4. DRY TJ: Hemochromatosis: its relation to the metabolism of iron and copper, Minnesota Med., 1934, xvii, 301. Google Scholar5. FOWLERBARER WMAP: Iron metabolism in hemochromatosis, Jr. Lab. and Clin. Med., 1937, xxiii, 47. Google Scholar6. SHERMAN HC: Chemistry of food and nutrition, 1932, The Macmillan Co., New York. Google Scholar7. FARRAR GE: The determination of iron in biological materials, Jr. Biol. Chem., 1935, cx, 685. CrossrefGoogle Scholar8. KENNEDY RP: The quantitative determination of iron in tissues, Jr. Biol. Chem., 1927, lxxiv, 385. CrossrefGoogle Scholar9. ELVEHJEMHART CAEB: Iron in nutrition. II. Quantitative methods for the determination of iron in biological materials, Jr. Biol. Chem., 1926, lxvii, 43. CrossrefGoogle Scholar10. PETERSVAN SLYKE JPDD: Quantitative clinical chemistry. II. Methods, 1932, Williams and Wilkins Co., Baltimore, p. 827. Google Scholar11. FOLIN O: Laboratory manual of biological chemistry, 5th edition, 1934, D. Appleton-Century Co., New York. (a) Colorimetric method for determination of ammonia, p. 141. (b) Micro Kjeldahl colorimetric method for the determination of total nitrogen in urine, p. 145. (c) Colorimetric determination of creatinine in urine, p. 159. Google Scholar12. LEICHSENRINGFLOR JMIH: The iron requirement of the pre-school child, Jr. Nutr., 1932, v, 141. CrossrefGoogle Scholar13. REZNIKOFFTOSCANIFULLARTON PVR: Iron metabolism studies in a normal subject and in a polycythemic patient, Jr. Nutr., 1934, vii, 221. CrossrefGoogle Scholar14. OHLSONDAUM MAK: A study of the iron metabolism of normal women, Jr. Nutr., 1935, ix, 75. CrossrefGoogle Scholar15. LEVERTONROBERTS RMLJ: The iron metabolism of normal young women during consecutive menstrual cycles, Jr. Nutr., 1937, xiii, 65. CrossrefGoogle Scholar16. SHELDON JH: Hemochromatosis, 1935, Oxford University Press, London. Google Scholar17. DRY TJ: Hemochromatosis: its relation to the metabolism of iron, Proc. Staff Meet. Mayo Clinic, 1933, viii, 56. Google Scholar18. SHERMAN HC: Chemistry of food and nutrition, 1932, The Macmillan Co., New York, p. 310. Google Scholar19. MURPHYLYNCHHOWARD WPRIM: The value of determinations of the iron content of whole blood, Arch. Int. Med., 1931, xlvii, 883. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Boston, Massachusetts*Received for publication February 28, 1938.From the George F. Baker Clinic, Elliott P. Joslin, M.D., Medical Director, New England Deaconess Hospital, Boston.This work was aided by a grant from the Chemical Foundation, Inc. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySt�rungen von Transportvorg�ngen als Ursachen von Krankheiten und von KrankheitssymptomenKrankheiten des KohlenhydratstoffwechselsTHE TREATMENT OF HEMOCHROMATOSIS BY MASSIVE VENESECTION*W. D. DAVIS JR., M.D., F.A.C.P., W. R. ARROWSMITH, M.D.PHLEBOTOMY FOR HÆMOCHROMATOSIS EFFECT OF REMOVING 52 PINTS OF BLOOD IN SIXTEEN MONTHSBeitr�ge zur Kenntnis des Eisen- und Kupferstoffwechsels im KindesalterLipemia in HemochromatosisOn the Metabolism of Iron in HemochromatosisIsolierte Hämochromatose der Haut bei Morbus Wilson 1 April 1939Volume 12, Issue 10Page: 1592-1603KeywordsHemochromatosisHospitalsPatientsUrine Issue Published: 1 April 1939 PDF downloadLoading ...