March 1, 1955Blood

Fundamental Observations on the Production of Compensatory Polycythemia in a Case of Patent Ductus Arteriosus With Reversed Blood Flow

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Population

A single case of patent ductus arteriosus occurring distal to the origin of the left subclavian artery with…

Design

Case_report

Authors

RSRudi SchmidBoston University AGA. Sigrid GilbertsenUniversity of Minnesota

Discussion

Member takes

Implication

Local marrow anoxia may not directly drive erythropoiesis; single case leaves humoral factor hypothesis open for prospective testing.

Structured PICO

Population

A single case of patent ductus arteriosus occurring distal to the origin of the left subclavian artery with persistent reversal of flow through the shunt and compensatory polycythemia

Intervention

Studies of cellular morphology and oxygen saturation of the bone marrow in the sternum and ilium

Outcome

Cellular morphology and oxygen saturation of the bone marrow in the sternum and iliumsurrogate

This case study demonstrates that bone marrow anoxia is not the direct stimulus for increased erythropoiesis, supporting the theory that blood anoxemia stimulates a humoral factor.

Cite This Study

Schmid et al. (1955) studied this question.

synapsesocial.com/papers/6a9067f678e5b5cd58dd79c6 https://doi.org/10.1182/blood.v10.3.247.247

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Fundamental Observations on the Production of Compensatory Polycythemia in a Case of Patent Ductus Arteriosus With Reversed Blood Flow

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Fundamental Observations on the Production of Compensatory Polycythemia in a Case of Patent Ductus Arteriosus With Reversed Blood Flow

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider