Toxic principles in the venom of the spider, Nephila maculata, were purified with the reverse phase high performance liquid chromatography, and three kinds of the major toxins (NSTX-1, -2 and -3) were isolated. These principles commonly possessed 2,4-dihydroxyphenylacetyl-asparaginyl-cadaveryl moiety in the molecule. The structure of NSTX-3 was concluded to be N-(2,4-dihydroxylphenylacetyl-L-asparaginyl)-N'-(L-arginyl-putreanyl)cadaverine.
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Aramaki et al. (1987) studied this question.
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