Why the study?
Does prophylactic vaccination favour the development of poliomyelitis?
Population
76 cases of poliomyelitis admitted in St. Sophie Children's Hospital during the autumn of 1950
Design
Case_series
Follow-up
2-14 days between vaccination and paralysis
Authors
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May associate recent vaccination with limb-specific paralysis localization; hypothesis-generating and should not change practice.
Does prophylactic vaccination favour the development of poliomyelitis?
This early case series suggests a potential association between recent mixed vaccination and the localization of poliomyelitis paralysis in the vaccinated limb.
Choremis et al. (1953) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: