PID surveillance identifies asymptomatic iVDPV excretors missed by AFP systems; leaves open whether expanded screening advances eradication.
Background: If exposed to oral poliovirus vaccine (OPV), persons with primary immune deficiency disorders (PID) are at increased risk of paralytic poliomyelitis; and can chronically excrete poliovirus. However, the risk of excretion of vaccine derived poliovirus among immunodeficient persons (iVDPV) is not well characterized. We present summary of data from poliovirus surveillance project among PID patients collected between 2011 and 2014 from 11 Egyptian Governorates.
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Sayed et al. (2016) studied this question.
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