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The initiation of germination of spores of Bacillus cereus was induced by L-alanine or L-phenylalanine and a combination of the amino acids showed an additive effect. Several compounds such as β-phenethylamine, phenylacetonitrile, benzyl alcohol, and phenethyl alcohol inhibited the initiation mechanism. The initiation of germination by L-alanine was more sensitive to β-phenethylamine while the L-phenylalanine induction was more sensitive to phenethyl alcohol. Selected antibiotics, known to block macro-molecular syntheses, were not effective as inhibitors of initiation. The results suggest that the receptor site may be compatible with an allosteric enzyme model and β-phenethylamine and phenethyl alcohol act as allosteric effectors.
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Wolgamott et al. (1971) studied this question.
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